19 Jul Niclosamide capsules
Niclosamide capsules (CAS No. 50-65-7) are a derivative member of the salicylanilides class of drugs. They are cream-colored and have a chemical formula of C13H8Cl2N2O4. Niclosamide capsules are used to treat tapeworm infections. They are available in 500mg capsules. Niclosamide capsules should be stored in their original packaging at room temperature.
Niclosamide capsules are taken orally. The recommended dosage for adults is 500mg two times a day. For children, the recommended dosage is 25-50mg/kg two times a day. Niclosamide capsules should be taken with food.
Common side effects of niclosamide capsules include nausea, vomiting, diarrhea, and abdominal pain. If you experience any of these side effects, contact your doctor. Niclosamide capsules are contraindicated in patients with hypersensitivity to the drug. Niclosamide capsules should be used with caution in patients with liver disease.
If you are pregnant or breastfeeding, talk to your doctor before taking niclosamide capsules. Talk to your doctor before taking niclosamide capsules if you have any other medical conditions. Niclosamide capsules can interact with other medications. Tell your doctor about all the medications you take, including over-the-counter drugs, vitamins, and herbal supplements. This includes prescription and over-the-counter medicines, vitamins, and herbal supplements.
Niclosamide capsules are biologically active when taken orally. Research has shown that niclosamide capsules inhibits the microtubule assembly within the cell. By inhibiting the microtubule assembly, niclosamide capsules inhibits the formation of new tubulin molecules which are necessary for cell division. By inhibiting cell division, niclosamide capsules decreases the number of tapeworms that can infect a human host.
Niclosamide capsules are made of the drug niclosamide. The drug is a derivative member of the salicylanilides class of drugs. Salicylanilides are a class of quinoline compounds that contain an aromatic ring with a nitrogen and two methyl groups linked by an ethylene double bond. They also contain an amino group attached at R1 and two alkyl groups attached to the same carbon atoms as the amino group, R4 and R5.
Technical details of Niclosamide Capsules
Niclosamide capsules (chemical formula C13H8CI2N2O4) is a derivative member of salicylanilides. It is cream colored.
- Synonyms: 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide;
- Formula: C13H8CI2N2O4;
- Molecular weight: 327.12 g/mol;
- ChemSpider ID: 4322;
- ChEMBL ID: 1448;
- ATC code: P02DA01 (WHO);
- PubChem CID: 4477;
- Average mass: 327.120 Da;
- Monoisotopic mass: 325.986115 Da;
- Melting points: 216-230 ℃;
- Solubility: DMSO <1 mg/mL; Water <1 mg/mL;
- HPLC analysis made by Adisant LTD using a Thermo UltiMate 3000 HPLC System;
Niclosamide capsules should be kept in its original packaging at room temperature. The melting point ranges from 216-230 ℃.
There are a few techniques that can be used to check the purity of niclosamide. One common method is to use thin layer chromatography (TLC). TLC is a method where a sample is applied to a plate coated with a thin layer of adsorbent material. The plate is then placed in a developing chamber containing a solvent. As the solvent moves up the plate, it will carry the sample with it. The sample will then separate into different components based on their solubility in the solvent. Once the plate is removed from the chamber, the different components will appear as separate spots on the plate. The purity of the sample can then be determined by comparing the number of spots on the plate to a known standard.
Another method that can be used to check the purity of niclosamide is high performance liquid chromatography (HPLC). HPLC is similar to TLC, but the sample is injected into the system under high pressure. This allows the sample to be separated into its different components much faster than with TLC. The purity of the sample can then be determined by comparing the peak areas of the different components to a known standard.
Niclosamide capsules are a derivative member of the salicylanilides class of drugs. Niclosamide capsules should be stored in their original packaging at room temperature. Niclosamide capsules should be taken with food. Common side effects include nausea, vomiting, diarrhea, and abdominal pain. If you experience any of these side effects contact your doctor.